The RHA® Collection is Resilient Hyaluronic Acid, dermal fillers designed for facial dynamics and represents the latest advancement in hyaluronic acid (HA) technology in more than a decade, using a gentle manufacturing process to more closely resemble the natural HA in the skin.

The RHA® Collection is the first and only FDA-approved hyaluronic acid fillers for dynamic wrinkles and folds and include three approved formulas: RHA® 2, RHA® 3, and RHA® 4.

The RHA® Collection of hyaluronic acid fillers are the only FDA-approved hyaluronic acid fillers for dynamic wrinkles and folds. Like other HA dermal fillers, RHA® is made from hyaluronic acid—but RHA® is different, because it’s made differently. RHA® uses a gentle manufacturing process. This process helps preserve the natural structure of the HA, helping it mimic the natural HA found in your skin. RHA® is the latest advancement in HA filler technology, purposely designed to perform in the most dynamic areas of the face without looking stiff or unnatural.

Results from your RHA® Collection are immediate. RHA® Collection delivers natural looking results, for dynamic areas of the face.

The RHA® Collection is designed to be long lasting—with proven clinical effectiveness and duration up to 15 months.

Indication and Important Safety Information

Approved Use

The RHA® Collection of fillers is for injection into the facial tissue for the correction of dynamic facial wrinkles and folds that are moderate to severe, such as nasolabial folds, in adults 22 or older.

IMPORTANT SAFETY INFORMATION

Are there any reasons why I should not receive any RHA® injectable gel formulation?

Do not receive if you have a history of multiple severe allergies or severe allergic reactions; if you are

allergic to lidocaine or gram-positive bacterial proteins; or if you have a bleeding disorder.

What precautions should I discuss with my doctor?

Tell your doctor if you are pregnant or breastfeeding as the safety of these products for use during

pregnancy or while breastfeeding has not been studied.

Tell your doctor if you have a history of excessive scarring, keloid formations or pigmentation

disorders, as use of these products may result in additional scars or changes in pigmentation.

Tell your doctor if you are planning laser treatments or a chemical peel, as there is a possible risk

of inflammation at the treatment site if these procedures are performed after treatment.

Tell your doctor if you are on immunosuppressive therapy used to decrease your immune

response, as use of these products may result in an increased risk of infection.

Tell your doctor if you are using medications that can prolong bleeding, such as aspirin,

ibuprofen, or other blood thinners, as this may increase bruising or bleeding at the injection site.

The safety and effectiveness of RHA® fillers in areas other than those indicated have not been

established in U.S. clinical studies.

Patients who experience skin injury near the site of injection with this product may be at a higher

risk for side effects.

Minimize strenuous exercise, exposure to extensive sun or heat, and alcoholic beverages within

the first 24 hours following treatment.

What are possible side effects?

The most commonly reported side effects included injection-site redness, swelling, pain, tenderness, firmness, lumps/bumps, bruising, discoloration, and itching.

One of the risks with using these products is unintentional injection into a blood vessel, and while rare, the complications can be serious and may be permanent. These complications, which have been reported

for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring.

As with all skin injection procedures, there is a risk of infection and recurrence of herpetic eruptions.

To report a side effect with any RHA® product, please call Revance at (877) 373-8669. Please visit RHACollection.com or talk to your doctor for more information.

Available by prescription only.